Announcement: “The CureCoin Project” Phase 1 Fiscal Sponsorship Complete
“The CureCoin Project” has fiscal sponsorship from Visions Made Viable, a 501(c)3 nonprofit organization (tax ID number: 26-2214003). Fiscal sponsorship means that The CureCoin Project has legal and tax exempt status under a sponsoring organization which has agreed to offer us nonprofit status for donations administration. Our fiscal sponsor is Visions Made Viable, a 501(c)3 non-profit based in California and committed to helping seed projects launch, and many of which “spin-off” to become independent non-profits.
Now you can support/donate to the CureCoin Project’s “Private Cloud Folding” systems with tax deductible contributions – 90% of which go directly to supporting computational power towards Protein Folding Research on [email protected] to help scientists study diseases like Cancer, Alzheimer’s, Parkinson’s, HIV and other very serious genetic, viral and bacterial diseases. Thanks to blockchain technology, the resulting CureCoin digital currency, exchange symbol [CURE], will be used to extend the non-profit portion of the CureCoin Project private Cloud Folding systems in our Bay City, MI US facility, in addition to funding our selected charities through Visions Made Viable*.
Legacy Giving System
Accept Deductible Donations (Cash, Paypal, retail giving like Amazon Smile) to fund Cloud Folding*
Selecting Visions Made Viable in your Amazon Smile account ensures 90% of Amazon’s contribution of your purchase price goes towards groundbreaking
Protein Folding research in our private cloud.
Adding Award Winning Research To Your Amazon Order Is Now Free!
Accept Deductible Bitcoin and Altcoin donations to fund Cloud Folding (coming soon)
Accept Deductible CureCoin donations to fund Selected Charities (coming soon)
Future Cloud Folding Expansion “A” ETA 2017
Future Cloud Folding Expansion “B” ETA 2017
Donation funds submitted to “CureCoin” must be sent through Visions Made Viable, who manages and oversees our finances according to our budget. See figure and donation information below.
You can make a tax deductible contribution to support The CureCoin Project’s Cloud Folding via PayPal donation through ‘Visions Made Viable’ or ‘CureCoin ‘ to either:
Or, you can make a tax deductible contribution to support the work of CureCoin by sending a check payable to:
Visions Made Viable
17595 Harvard Ave.
Irvine, California 92614
(please add Attn: CureCoin in the notes section of your check)
*CureCoin digital currency produced via The CureCoin Project’s private Cloud Folding systems will either be converted and re-invested into the Cloud Folding systems, or donated to our sponsored charities through Vision’s Made Viable at The CureCoin Project’s discretion. A quarterly report will be furnished to show how much was received, how many [email protected] computational points (PPD) were generated by the project, and how much was donated to our selected charities. Merged Folding will be utilized to maximize computational output and maximize donations for our selected charities through Visions Made Viable.
The non-profit CureCoin Project Private Cloud Folding rack is ready to contribute to research with the help of your generous donations. The CureCoin LLC public for-profit Cloud Folding store is currently being re-designed cloudfolding.curecoin.net with an ETA of mid-December for those who want to commission convenient cloud folding to generate their CureCoins.
Contributions to The CureCoin Project are tax deductible to the extent allowed by law and its fiscal sponsor, Visions Made Viable, provided no goods or services for your contribution.”
More tax deductible giving options using Bitcoin and Altcoin digital currencies will be deployed through Coinpayments.net in the coming weeks!
Great news for all of the folks on team Curecoin who fold proteins using their PC’s, Macs and Laptops (and everyone watching from the sidelines). Looking at our “stats”, you’ll notice something spectacular. With speeds blazing over 14 petaFLOPS*, our team has managed to secure a SOLID #3 Ranking on [email protected]’s (FAH) global network. FAH has a 16 year history with over 1.7 million registered accounts. Within that framework, the CureCoin team has outperformed the combined efforts of top individuals and several corporate sponsored teams – including Google (thanks in part to our collaboration with FoldingCoin) . Today, one CURE digital coin represents over 28,000 PPD** worth of computational research! The Curecoin team wants to tip our hats and send all of you a virtual round of applause…
We’d like to take a moment to send a shout-out to one of our folders. Special thanks to Mr. Ed Olkkola, username “PS3EdOlkkola”, for continuing to help make team Curecoin pump out MASSIVE computational research numbers! At nearly 12 billion points and counting Mr. Olkkola now holds 1st place for individual points earned on the entire [email protected] network – even surpassing all anonymous contributors combined.He continues a friendly competition with another folder going by username “war” however; with 2 data centers and custom systems configured by Ed Olkkola himself, he has managed to prove he’s winning the battle with an average of 31 million points per day! Since all this computational research helps the advancement of medicine, we all become winners in the process.
Again, we just want to take a moment to congratulate everyone on team Curecoin for this amazing accomplishment. Combined we’re contributing of over 14% of the total network speed for [email protected] – that’s not too shabby. To all of you reading this who are NOT currently folding, it’s not too late to get in on the action. Just head over to curecoin.net to get started today!
Thanks and Happy Folding,
The CureCoin Team
The CureCoin team is a protein folding team 224497 on the Stanford University worldwide [email protected] network. The CureCoin blockchain and CURE alternative currency reward system are independent from Stanford School of Medicine.
* Percentage of overall petaFLOPS does not factor in Quick Return Bonus (QRB) points
** (Team CureCoin Total PPD) / 7488
The CureCoin Team converted 100,000 CURE donated by our contributors into $2500 USD … to donate some of your CURE, see “Donate CureCoins”
A kind -Thank You- to everyone who contributed to our causes during this round of donations, but a very special acknowledgement goes to our current folding champion, Mr. Ed Olkkola. He has directed our team to process all his coins into donations to charities like ANTRUK, Bonfils Blood Center, Rwanda Dream Medical Clinic, Stanford’s Pande Labs, and others in the name of the CureCoin Team. All his coins are generated thru large-scale contributions of computational power to [email protected]’s search for new medicines (over 20,000,000 [email protected] points per daywhich equates to about 700 CureCoins per day!) Mr. Olkkola’s computing power comes from custom-built servers of his own design, owned and maintained in two data centers; one at Mr. Olkkola’s residence, and the other at his company’s facility. Incredibly the theoretical costs of doing this much computational biology using the most popular HPC cloud services (like Amazon AWS or Google Compute Cloud) equates to about $1700/day OR amazingly over $600,000 per year!
Over the years, Mr. Olkkola’s dedication to Stanford’s Pande Labs advancement in the search for new medicines, as well as his charitable giving through CureCoin demonstrates multidimensional levels of philanthropy. This not only inspires members of the [email protected] community, but also those joining us with their laptops for the very first time.
Antimicrobial Research UK
ANTRUK, the world’s first charity tackling antimicrobial resistance, was established by a network of leading UK scientists and clinicians with the mission to educate the public about microbial resistance, promote the discovery and development of new antibiotic therapies, and support those currently living with antibiotic-resistant infections.
For over 50 years, the discovery of a new class of antibiotics has evaded the industry and the threat of antimicrobial resistance has ever increased. Recently, the former Goldman Sachs Chief and now UK Commercial Secretary to the Treasury, Lord Jim O’Neill, released his final report, which was part of a two-year Antimicrobial Resistance Review. This report highlighted the enormous need for new business models to fund and incentivise the discovery of new therapies to treat drug-resistant infections.
“If the rise in resistance continues at the current rate, ten million people will die each year by 2050 and Gross Domestic Product will fall by 2-3.5% — costing the world up to $100 trillion.” – Wired UK
Bonfils Blood Center
Colorado based Bonfil’s blood and marrow donation centers recently announced a merger with the national Blood Systems, Inc.
In this round, donations to Bonfil’s Blood Centers are going towards Everyday Lifesaving Operations and Transfusion Medicine Excellence Research.
Donations to “Everyday Lifesaving Operations” provide unrestricted funds that can be allocated when and where they are needed most. General operating support is often utilized to meet unforeseen emergencies, provide timely support for programs and equipment that allow Bonfils to better serve the hundreds of thousands of patients they help annually.
Donations to “Transfusion Medicine Excellence” achieve rigorous testing of blood and blood products to ensure safety, maintaining Bonfils’ status as a state-of-the-art blood center – adopting new technologies and staying abreast of the industry’s best practices.
Donors can designate their gift to any one or all of the following initiatives:
* Blood Supply and Patient Safety
* Laboratory Equipment
* Employee Skills Training
* Facilities Improvements
Dream Medical Center Rwanda
For the New Life Rwanda Dream Medical Clinic, CureCoin converted our donated CURE to USD. Donations contribute to helping establish a new medical center in Rwanda through Africa New Life:
* The center will be open to the public, adding important medical bandwidth to Kigali.
* Provide modern surgical, postoperative, and rehabilitative care for the people.
* A hub for Africa New Life Medical – provide full-time nurses to watch over 7K children.
Through this, we not only raise awareness for [email protected], but we also demonstrate how Curecoin can fund charities on a global scale. Special thanks to those who donated to our fund.
ThumbsUp! International is a non-profit organization created to connect people across all abilities to conquer athletic challenges together, expanding attitudes about possibilities by embracing life’s challenges. We team able and disabled athletes to maximize their potential.
* … adaptive athletes compete with physically abled athletes in swimming, biking, running & triathlon events
Those of you who follow us may have seen us with Kerry Gruson, co-founder of ThumbsUp International in Miami. We recently noticed that their web page was down, so our founder Joshua Smith coordinated with the very gracious staff at ThumbsUp to get the site www.thumbsupintl.org back up with the ability to accept USD donations (click Support Us). While on the new webpage, we contributed converted CureCoins – with more donations scheduled in the future.
Kerry Gruson’s story is especially inspirational. She is a former New York Times correspondent who covered some of the most pivotal moments in US history. She also worked for the Harvard Crimson, Boston Phoenix and the Boston Globe. Kerry continued to work despite her disability (sustained in 1974), all the way to her retirement in 2005. You can watch her story here
Toni Lane Casserly the co-founder of both online bitcoin publication CoinTelegraph and Kids Compassion Charity. In a recent conversation with Toni, we were convinced Kids Compassion is doing great work in Sierra Leone, a country recovering from the recent Ebola epidemic.
As a “TLC” and Mustapha Cole project, Musta was inspired to start a charity after realizing how many children lost their entire families to the Ebola crisis. Having lived through and having experienced Ebola first hand, he has seen how hard it is for children who are developing in elementary school ages to maintain stability and focus on the future through this chaos and loss. To rebuild these incredible children, Musta recruited TLC to form Kids Compassion Charity. They have since hand selected a high potential group of kids without families to provide these fertile minds with a home, a sense of belonging and higher moral / traditional education.
“We are starting small. Our first goal is to build out one school in Sierra Leone. When we are able to effectively care for the kids in this community, we plan to expand operations to help children throughout the continent have a safe space where they can thrive. Our education program focuses on entrepreneurial skills, technology, integrity, language and love.”
The July 2016 donation to fund servers at Stanford’s Pande Labs / [email protected] brings the total amount of USD donated to Pande Lab’s to nearly $8,000 since CureCoin’s inception. We will continue to support [email protected] and helping fund Stanford Pande Labs equipment going forward. Great job to all donors making these donations possible!
Exchange Rates and Costs of Folding
As planned, the donated CureCoin (symbol CURE) plus their associated stake earnings were sold thru Bittrex, Livecoin or Poloniex exchanges. After conversion to USD they have been donated to above causes throughout July, 2016. To get the average exchange rate of CURE to BTC, consult Coingecko.
Do you want to understand the costs behind producing this much research on [email protected]?
* See our cost estimator spreadsheet from Dec 2015 showing 12 Equipment profiles.
You may be surprised just how serious distributed computing can be 🙂
CoinPayments.net accepts over 55 cryptocurrencies, giving Curecoin a *potential to reach a trusted network of over 31,000 registered vendors around the world (*our vendor list is modest but growing). CoinPayments gives buyers and sellers peace-of mind through protected, secured transactions. Register your business to accept CURE today at CoinPayments.net Register!)
Everyone is encouraged to promote the usefulness of Curecoins as a means of P2P exchange for goods and services, or as a means to donate to a good cause. Nothing prevents you from asking vendors and service providers you know, if they would consider full or partial payment in CURE.
Although we’d like to take more credit, it’s humbling to be part of a global movement of teams and individuals so committed to Protein Folding research. A lot of work remains on our part to catapult the CureCoin Team to the #1 ranking – although we have managed to reach the #4 spot in under two years – beating out several large corporate-sponsored teams along the way. We envision a combination of corporate and cryptocurrency mining community interest in CureCoin are the keys to accelerating research going forward.
“We’re pushing to design drugs that are (disease) selective at higher doses, without side effects that almost kill patients” – Vijay Pande (Paraphr. CoinDesk 2013 article)
“…techniques that we develop here very naturally have been applied to cloud computing, further broadening the impact of FAH’s scientific impact.” [email protected] blog 2016 projections
…So how does “Protein Folding” help?
Drug design has traditionally been slow, costing 100’s of millions of dollars, and is prone to stalling in Phase II trials. In projects like [email protected], the rewards are long-term. In-silico research is done at the earliest stages of the FDA drug approval process (see figure below). In addition to the study of multiple diseases (both infectious, and proteopathy in which proteins become structurally abnormal), [email protected]’s focus is on researching protein folding dynamics. Since proteins spend up to 96% of folding time “waiting” in various “intermediate conformational states”, there are countless, as yet undiscovered molecular interactions – especially those related to drug design.
… So the answer to the original question is – “it’s complicated” – but read on for a great example:
Historical perspective using a series of Alzheimer’s Disease Studies
The drug was promising in animal models, however it failed in Phase II human trials due to a development of toxicity
Despite this setback, the same FAH research continues to be cited by 23 studies – not all related to Alzheimer’s.
Starting in 2015 those results are part of an ongoing research project to re-purpose an existing compound(video from ICME Xpo Talk) for use as an Alzheimer’s treatment!
Protein folding creates more opportunities in the early phases of drug design as well as enzyme research. As more computational power is added by contributors, the more “super complex systems” (like ion channels) can be explored in ways not possible a decade ago.
Acknowledgement of the [email protected] community in Pande Lab Scientific Papers since 2014
CureCoin Cryptocurrency Update (SigmaX and CC 2.0):
Earlier this year, CureCoin announced a change in direction for CureCoin 2.0. Rather than having a single coin, the new blockchain will result in two coins. One will be CureCoin 2.0 (purely based on folding), the other will be a traditional PoW model called SigmaX. While both will share the same decentralized blockchain model, and both will be quantum resistant and utilize Merkle Tree Signatures; SigmaX is being developed for those who feel CureCoin’s dependency on signing certificates from DCN research lacks the purity required to compete in a decentralized cryptocurrency market on its own. CureCoin holders will be allowed to participated in SigmaX based on their holdings. You can read all the details and join the sometimes colorful conversation on our bitcointalk thread
CureCoin is now available to trade on LiveCoin.net (and trading with our long time partners at Bittrex.net and Poloniex exchanges). Additionally CureCoin is listed on the CoinPayments.net marketplace which gives CureCoin the *potential* to reach a trusted network of over 31,000 registered vendors around the world. As part of the latest Fintech infrastructure, CoinPayments gives buyers and sellers peace-of mind through protected, secured transactions. Register your business to accept CURE today at CoinPayments.net!
A special acknowledgement to our top folder – Ed Olkkola, whose massive donations of CURE (generated purely from his folding activities) are helping, or have helped fund donations to ANTRUK, Bonfils.org, Pande Labs, U-foundation Zambia, and the Rwanda Dream Medical Center. We’ve chosen to start converting Ed’s donations on the markets dynamically, so you wont see a large lump-sum of coins in the donation wallets which could impact the market price if they’re sold off too fast.
Please feel free to join us on the CureCoin IRC Channel for anything that’s on your mind: A new secure bot is back online, and tipping is available.
Also, we’ve found some members use bitcointalk and other social media sites for technical support issues. If at all possible, please use our support forum instead. This helps us track tech support issues in one place, and makes them searchable for everyone with similar questions.
This includes Ed’s generous donations to our experimental crowdfund for Endometriosis Research. Although the fund did not reach the required critical-mass, we learned so much, and we want to continue experimenting with alternative research funding in the future. We helped raised awareness; not only for Folding @ Home, but for the potential of CureCoin to fund new research. Most importantly, we helped put a spotlight on the disease itself, and on the need to help the millions who suffer from its debilitating consequences. Thank you to everyone who viewed our pages and helped us craft a reasonable approach to the research.
As planned, the donated Curecoin (symbol CURE) plus their associated stake earnings have been sold thru Bittrex and Livecoin exchanges, as well as thru private sales. After conversion to USD they have been donated to [email protected] in three transactions throughout February, 2016.
U-Foundation Zambia (helping others to help themselves)
Through a private sale, Curecoin converted CURE to BTC and GBP. Using Virgin Money Giving we contributed to help U-Foundation support projects like Siankaba and Mutakwa Village Projects:
* Updating medical clinics to support thousands of villagers from surrounding areas.
* HIV/AIDS is a major concern in the area.
* Adding to that the threat of Ebola and clinics become not only the central point of treatment but also of education.
* Building nurseries to house up to 50 newborns and nursery schools for youngsters.
* Refurbishing Middle Schools, providing books, book bags and sports equipment.
* Some students walk up to 30km per day to attend school.
* Agricultural education – establish teaching farms to help create local, sustainable farming.
New projects include Tailoring – teaching students the apparel manufacture process.
Through this, we not only raises awareness for [email protected], but demonstrates how Curecoin can fund charities on a global scale as a result. Special thanks to those who donated to our fund.
It has not been quite a year, and about 2 weeks ago Team CureCoin has made it to Rank #4 in worldwide folding power contributions on the Folding @ Home network, the largest researched based DCN on earth. This goes to show people in the crypto community have the powerful setups and knowledge of cloud computing to really get some work done! There are a number of members on our team that have hopped team but some of the most powerful to come through, have come from the crypto community.
What does this mean for the future of crypto and research DCN’s? Well, one thing is for sure, Team CureCoin intends to find out! With CureCoin 2.0 about to have public beta testing soon, and the coming full launch of the CureCoin cloudfolding systems, we expect to see more and more participants hop on board. We are reaching out to many events in order to show people that folding for FAH can not only be rewarding in the sensation of helping humanity, you can be rewarded with crypto “Cure”ncy as well.
Our own Ivan Tuma Jr has just made a trip to another conference just last night to UCLA , expect a report from him soon. In the mean time let’s celebrate rank #4 as a team! Great job folders big and small!
With the 1 year anniversary of the original launch date coming up, CureCoin has proven to be a worthy cryptocurrency! With many coins coming and going in the blink of an eye, we are still going. Look forward to more exciting developments as time goes on and Team CureCoin prevails!
Donate CureCoin to fund an Endometriosis Pilot Study on the Folding @ Home Network
The donation campaign for this project has ended and funds have started to be converted. We will be updating our site with new campaigns soon
You can read more about the results of this campaign on the forum here
Recent data indicates that over 170 million women of reproductive age world-wide suffer debilitating pain and infertility from Endometriosis. “Endo” is linked to protein mis-folding, however there is no scientific consensus on its root cause. Theories include stem cells, genetics, and immunological factors. Women whose mothers suffered from “Endo” are up to 7 times more likely to exhibit symptoms themselves.
The ultimate goal of this study is to create minimally invasive, yet deterministic tests for Endometriosis pre-menarche (before first menses). Pre-teens at risk could be tested, and subsequently make lifestyle adjustments to prevent premature menarche, in addition to treatment with Combined Oral Contraceptives (COCs) early in puberty to dramatically reduce the risk factors of retrograde menstruation and Endometriosis. In rare cases – more aggressive treatments via puberty-suppression therapy could be explored.
Many girls with Endo enter puberty too early, while their BMI is still too low (min. BMI requirement for menarche is 23.7% ). Studies indicate worldwide age of menarche has fallen from 16-17 down to <13 as a possible byproduct of EDC (Endocrine-Disrupting Chemical) exposure. Although there are no known bio-markers for Endo (pre-menarch), we strongly feel computational biology can be leveraged to explore peripheral theories covering early menarche so "Endo" can be minimized or even prevented in future generations of young women.
More discussion can be found on reddit at /r/Endo
This fund is the first of it’s kind, attempting to showcase the potential of CureCoin to help finance new research. Beginning a new study on [email protected] requires more than just computational power. Pande Labs would need manpower on the back-end to analyze the computational results – then conduct new experiments based on that analysis.
Update: We are officially extending the deadline for this study from 07.31.2015 to 10.30.2015. We’ve begun investigating public crowdfunding (Indiegogo, Crowdster, etc.), foundations and celebrities. If significant funds are not collected by the new expiration date, the collected coins will be rolled into a general Folding @ Home Donation Fund. (See “Donate CureCoins” tab at the right for CURE donation addresses).
Fast Track for Beginners – Download the Folding Browser FoldingCoin has made it easy to get started merge-folding by having your FAH installer and your wallet download as a configurable set…
The FoldingCoin Inc. team and the Curecoin team have recently had a conference call to discuss each of the projects. Though the infrastructure and protocols used for each coin differ, FoldingCoin Inc. and Curecoin are both dedicated to attracting more folders and miners into the [email protected] project.
Both teams openly shared different ideas of how to approach gaining more adoption to [email protected] and the various projects and features each are working on. The main goal here is to stop wasting energy on Altcoins that use energy for creating copycat Bitcoin blockchains.
Curecoin has made the decision to allow for longer usernames on their team (now limited to 50 characters, i.e. johnsmithII_ALL_2Hf6D8GHxDNJFVkaVk5RJrX6BhUB9Gx3zF <- this is your FLDC address, not to be confused with your CURE address on cryptobullionpools). This will allow FLDC participants to earn CURE alongside of FLDC and the other Merged Folding tokens on the FoldingCoin Inc. platform. Both teams decided that this would be a great option for the Folders looking to acquire both, as our teams are here for you the Folder and the [email protected] network as a whole. Due to the nature of the way FLDC and CURE are distributed, you cannot earn CURE if you are on any team but the Curecoin FAH team 224497.
FoldingCoin Inc. will continue to develop Bitcoin 2.0 technology and smart assets to be applied to [email protected] and Curecoin will continue to develop making strides in advancing independent blockchain technology to be applied to [email protected] FoldingCoin Inc. and Curecoin look forward to continuing a positive relationship sharing our ideas and accomplishments along the way with each other in hopes that it will attract further miners to become Folders.